Molecular Formula | C20H18O5 |
Molar Mass | 338.35 |
Density | 1.351±0.06 g/cm3(Predicted) |
Melting Point | 173-174 °C (decomp)(Solv: chloroform (67-66-3)) |
Boling Point | 583.5±50.0 °C(Predicted) |
Appearance | Yellow powder |
pKa | 6?+-.0.40(Predicted) |
Storage Condition | 2-8℃ |
Physical and Chemical Properties | Brown-red thick liquid, insoluble in water and various oil esters, soluble in ethanol, propylene glycol, glycerol and some organic solvents. Quality index: solid content ≥ 20%, licoridine ≥ 0.38%, heavy metal: ≤ 0.002%. Active ingredient:>0.35%, flavone test: positive. |
Reference Show more | 1. [IF=5.81] Chen Jia et al."Network Pharmacology-Based Strategy for Elucidating the Molecular Basis Forthe Pharmacologic Effects of Licorice (Glycyrrhiza spp.)."Front Pharmacol. 2021 Apr;0:872 2. [IF=3.935] Jia Chen et al."A general procedure for establishing composite quality evaluation indices based on key quality attributes of traditional Chinese medicine."J Pharmaceut Biomed. 2022 Jan;207:114415 3. [IF=2.406] Du Jinliang et al."Alleviative effects of total flavones of Glycyrrhiza uralensis Fisch on oxidative stress and lipid metabolism disorder induced by high-fat diet in intestines of Tilapia (Oreochromis niloticus)."3 Biotech. 2021 Jul;11(7):1-12 4. [IF=2.235] Du Jinliang et al."Regulatory effects of Glycyrrhiza total flavones on fatty liver injury induced by a high-fat diet in tilapia (Oreochromis niloticus) via the Nrf2 and TLR signaling pathways."Aquacult Int. 2022 Mar;:1-22 |
Plant Source: | licorice |
licorice flavonoids | licorice flavonoids is light yellow to white powder, with antibacterial, anti-inflammatory, antioxidant, anti-aging, UV absorption, whitening skin, freckle, inhibit tyrosinase activity, moisturizing, repair damaged skin, hair, widely used in cosmetics. |
natural herb | licorice flavonoids is a natural whitening agent extracted from a specific variety of licorice, which can inhibit the activity of tyrosinase, it can also inhibit dopa pigment interconversion and DHICA oxidase activity. It is a fast, efficient and green cosmetic additive for whitening and freckle removal. |
pharmacological effects | licorice flavonoids, glycyrrhizin, aspartame, mannitol, etc, the compound extracted from licorice, licorice flavonoids, has a variety of effects in beauty cosmetics. At the same time, licorice flavonoids also inhibit tyrosinase activity, remove oxygen free radicals, and have anti-inflammatory and anti-allergic effects, this mainly comes from the glycyrrhizic acid Iridium-glycyrrhizic acid and glycyrrhetinic acid salt, can also inhibit capillary permeability. also has adrenocortical hormone-like action, and licorice has mineralocorticosterol-like action and glucocorticoid-sterol-like action. The principle of its hormone-like effect, some people think that the chemical structure of glycyrrhetinic acid and adrenal cortex hormone have similar points, is a direct effect, but some people think that it is an indirect effect, that is, glycyrrhetinic acid inhibits the destruction of adrenocortical sterols in the body, and thus the blood content is correspondingly increased. at the same time, licorice flavonoids also inhibit tyrosinase activity, scavenging oxygen mesh by base, its antioxidant capacity and vitamin E is close to licorice flavonoids, tonic medicine contains protein and a variety of amino acids, refers to the class, polysaccharides, fruit acids, vitamins, trace elements, etc., which protein and hydrolyzed amino acids for cosmetics, the skin, hair nutrition and moisturizing effect, and has a repair effect on the damaged skin and hair. |
biological activity | Licoflavone C is a flavonoid compound obtained from the flower of the skin, can reduce the genetic toxicity of anticancer drugs. |